{"id":24435,"date":"2024-08-05T10:52:44","date_gmt":"2024-08-05T15:52:44","guid":{"rendered":"https:\/\/www.ataxia.org\/?page_id=24435"},"modified":"2025-07-25T16:31:13","modified_gmt":"2025-07-25T21:31:13","slug":"sca12","status":"publish","type":"page","link":"https:\/\/www.ataxia.org\/sca12\/","title":{"rendered":"SCA12"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"24435\" class=\"elementor elementor-24435\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-68a295e elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"68a295e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-14c7928\" data-id=\"14c7928\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-54cacf2\" data-id=\"54cacf2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d5fd68a elementor-widget elementor-widget-heading\" data-id=\"d5fd68a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-xl\">SCA12<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-06771b0 elementor-widget elementor-widget-spacer\" data-id=\"06771b0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1cdca19 elementor-widget elementor-widget-text-editor\" data-id=\"1cdca19\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong><span style=\"color: #000000;\">A collection of resources for individuals and families affected by Spinocerebellar Ataxia Type 12 (SCA12).<\/span><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3e99344 elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3e99344\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-c6f0740\" data-id=\"c6f0740\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ea0b722 elementor-widget elementor-widget-text-editor\" data-id=\"ea0b722\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"#SCA8webinars\"><strong>WEBINAR<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-138f32f\" data-id=\"138f32f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-631400f elementor-widget elementor-widget-text-editor\" data-id=\"631400f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"#SCA8factsheet\"><strong>INFORMATION<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-eabe373\" data-id=\"eabe373\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e24932d elementor-widget elementor-widget-text-editor\" data-id=\"e24932d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"#SCA8SCAsource\"><strong>RESEARCH NEWS<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-adf4334\" data-id=\"adf4334\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c451c91 elementor-widget elementor-widget-text-editor\" data-id=\"c451c91\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #ffffff;\"><a style=\"color: #ffffff;\" href=\"https:\/\/interland3.donorperfect.net\/weblink\/weblink.aspx?name=E79738&amp;id=285\" target=\"_blank\" rel=\"noopener\"><strong>BECOME A MEMBER &gt;&gt;<\/strong><\/a><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-27d68dc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"27d68dc\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fc91af7\" data-id=\"fc91af7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ad9054e elementor-widget elementor-widget-spacer\" data-id=\"ad9054e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-07ecc4a elementor-widget elementor-widget-text-editor\" data-id=\"07ecc4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Spinocerebellar Ataxia type 12 (SCA12) is caused by a genetic mutation that is passed on from parents to their children. SCA12 leads to problems with balance and coordination, as well as tremors.\u00a0<span style=\"color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">For complete information about symptoms, diagnosis, and treatment of Ataxia, visit our <\/span><strong style=\"color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\"><span style=\"text-decoration-line: underline;\"><a href=\"https:\/\/www.ataxia.org\/what-is-ataxia\/\" target=\"_blank\" rel=\"noopener\">What is Ataxia?<\/a><\/span><\/strong><span style=\"color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\"> page. This page contains NAF&#8217;s resources that are specific to SCA12.<\/span><\/p><p><strong><span style=\"text-decoration: underline;\"><a href=\"https:\/\/interland3.donorperfect.net\/weblink\/weblink.aspx?name=E79738&amp;id=285\" target=\"_blank\" rel=\"noopener\">Sign up for our mailing list<\/a><\/span><\/strong> to stay up-to-date on Ataxia news.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2f0c465 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2f0c465\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-90a900d\" data-id=\"90a900d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4ad773e elementor-widget elementor-widget-spacer\" data-id=\"4ad773e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d8aa660 elementor-widget elementor-widget-menu-anchor\" data-id=\"d8aa660\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"SCA8webinars\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3fe6bb5 elementor-widget elementor-widget-heading\" data-id=\"3fe6bb5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Webinar<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1ce4dbf elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"1ce4dbf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8644daf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8644daf\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-41b0c67\" data-id=\"41b0c67\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e710b04 elementor-widget elementor-widget-heading\" data-id=\"e710b04\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">All About SCA12<br>\n<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b12e6a2 elementor-widget elementor-widget-video\" data-id=\"b12e6a2\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/youtu.be\\\/sRYwFnZ0Pkg&quot;,&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c95d6b3 elementor-widget elementor-widget-text-editor\" data-id=\"c95d6b3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em><strong>Presented by Russell Margolis, MD <\/strong><\/em><\/p><p>During this webinar, Dr. Margolis looked at the causes and symptoms of Spinocerebellar Ataxia type 12 (SCA12), the typical diagnostic journey for those affected, what to expect for clinical care, and an overview of current research into the disease.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-49c1de2 elementor-widget elementor-widget-text-editor\" data-id=\"49c1de2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>NAF offers webinars on many topics to help you live better with Ataxia. Visit\u00a0<span style=\"text-decoration: underline;\"><a href=\"https:\/\/www.ataxia.org\/webinars\" target=\"_blank\" rel=\"noopener\">www.ataxia.org\/webinars<\/a><\/span>\u00a0to find other helpful presentations.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8a81c01 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8a81c01\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f4c6e4e\" data-id=\"f4c6e4e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-24842cb elementor-widget elementor-widget-spacer\" data-id=\"24842cb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-92f0028 elementor-widget elementor-widget-menu-anchor\" data-id=\"92f0028\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"SCA8factsheet\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-14c26b4 elementor-widget elementor-widget-heading\" data-id=\"14c26b4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">SCA12 Information<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-95c3ac2 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"95c3ac2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0f059b1 elementor-widget elementor-widget-text-editor\" data-id=\"0f059b1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Spinocerebellar Ataxia type 12 (SCA12) is a rare neurodegenerative disorder. It is caused by a CAG triplet repeat expansion in the PPP2R2B gene. SCA12 is very rare worldwide. However, SCA12 is very prevalent in Northern India. Approximately 16% of autosomal dominant ataxia patients in India have SCA12.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-741f45d elementor-align-center elementor-widget elementor-widget-button\" data-id=\"741f45d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2024\/08\/SCA12.pdf\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Printable Fact Sheet<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-04f6a13 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"04f6a13\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-aebbc4d\" data-id=\"aebbc4d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-71d8abb elementor-widget elementor-widget-heading\" data-id=\"71d8abb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">SCA12 Symptoms<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dca2ce0 elementor-widget elementor-widget-text-editor\" data-id=\"dca2ce0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span data-contrast=\"auto\">Like many other forms of Ataxia, SCA12 is marked by poor balance and coordination. In fact, the word Ataxia means incoordination. There can also be problems coordinating muscles that control speech and swallowing.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">The first symptom for many people with SCA12 is tremors in the head and arms. These tremors are called action tremors, they occur when muscles are being voluntarily used. Many people with SCA12 have neuropsychiatric symptoms, such as anxiety, depression, cognitive difficulties, and dementia.\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Less common symptoms of SCA12 include vision problems, eye spams, muscle contractions, increased reflexes, Parkinson-like symptoms, and neuropathy.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e8545b2 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e8545b2\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-bfe3bfa\" data-id=\"bfe3bfa\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d4ef250 elementor-widget elementor-widget-heading\" data-id=\"d4ef250\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">SCA12 Prognosis<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4186e65 elementor-widget elementor-widget-text-editor\" data-id=\"4186e65\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>SCA12 symptoms usually begin between the ages of 30 and 50. However, symptoms can begin as young as 8 years old and as late as 70 years old. The severity of symptoms also varies considerably, even within families.<\/p><p>SCA12 usually progresses very slowly. Lifespan generally is not shortened by the disease. Treatments such as mental health support, physiotherapy, occupational therapy, and speech-language therapy can significantly improve the lives of people with SCA12.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5546e49 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5546e49\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-49accc6\" data-id=\"49accc6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c8b141a elementor-widget elementor-widget-heading\" data-id=\"c8b141a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">SCA12 Genetics<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-058bf70 elementor-widget elementor-widget-text-editor\" data-id=\"058bf70\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span data-contrast=\"none\">SCA12 is a genetic disorder which means that it is an inherited disease. The abnormal <\/span><span data-contrast=\"auto\">gene responsible for this disease is passed along from generation to generation by family members who carry it. Genetic diseases like SCA12 occur when one of the body\u2019s 20,000 genes does not work properly. Genes are microscopic structures within the cells of our bodies that contain instructions for every feature a person inherits from his or her parents.\u202f<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">SCA12 is an autosomal dominant disease, meaning individuals of either sex are equally likely to inherit the gene and develop the disease. Each child of a person with SCA12 has a 50% chance of inheriting the gene that causes SCA12.\u202f<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">In the case of SCA12, it is caused by a mutation called a CAG repeat expansion in the\u202f<\/span><i><span data-contrast=\"auto\">PPP2R2B<\/span><\/i><span data-contrast=\"auto\"> gene. Whether or not you develop SCA12 depends on how many repeats you have.\u202f\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><ul><li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"7\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Between 4-31 CAG Repeats: This is the typical number of repeats in the <em>PPP2R2B<\/em> <\/span><span data-contrast=\"auto\">gene. People with this number of repeats are healthy.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li><\/ul><ul><li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"7\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">Between 32 and 49 repeats: Due to limited data, it is not clear what this number of repeats means. Some people may develop symptoms, others may not. There is active research to understand what this number of repeats does to the body, but right now it results in an uncertain diagnosis.\u00a0\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li><\/ul><ul><li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"7\" data-list-defn-props=\"{&quot;335552541&quot;:1,&quot;335559685&quot;:720,&quot;335559991&quot;:360,&quot;469769226&quot;:&quot;Symbol&quot;,&quot;469769242&quot;:[8226],&quot;469777803&quot;:&quot;left&quot;,&quot;469777804&quot;:&quot;\uf0b7&quot;,&quot;469777815&quot;:&quot;hybridMultilevel&quot;}\" aria-setsize=\"-1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">Over 50 repeats: <\/span><span data-contrast=\"none\">\u202f<\/span><span data-contrast=\"auto\">People with more than 50 repeats\u202fusually develop SCA12.\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li><\/ul><p><span data-contrast=\"auto\">More repeats are associated with an earlier age of onset of symptoms. \u202fUnlike some other forms of ataxia caused by repeat expansions, SCA12 repeats do not tend to expand or increase in number between generations.\u00a0<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Gene tests can be performed for diagnostic purposes to determine what kind of Ataxia is within a person or family. Genetic testing also can be done, in some circumstances, even before there are symptoms to determine whether a person carries the abnormal gene or genes that cause Ataxia. This is called predictive or presymptomatic testing. A gene test also can be used to determine whether a fetus has an abnormal Ataxia gene. This is called prenatal testing. Anyone who is considering a predictive or prenatal test should consult with a genetic counselor to discuss the reasons for the test, the possible outcomes, and how those outcomes might affect the person emotionally, medically, or socially.<\/span><span data-contrast=\"auto\">\u202f<\/span><span data-contrast=\"auto\">\u202f<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-65d6d84 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"65d6d84\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-13ffacd\" data-id=\"13ffacd\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3517368 elementor-widget elementor-widget-heading\" data-id=\"3517368\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">SCA12 Diagnosis<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-66e7ec8 elementor-widget elementor-widget-text-editor\" data-id=\"66e7ec8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun Highlight SCXW88890573 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"normaltextrun\" data-ccp-charstyle-defn=\"{&quot;ObjectId&quot;:&quot;884ca0a2-3096-4dd9-b9ad-d857f553f4df|107&quot;,&quot;ClassId&quot;:1073872969,&quot;Properties&quot;:[201342446,&quot;1&quot;,201342447,&quot;5&quot;,201342448,&quot;1&quot;,201342449,&quot;1&quot;,469777841,&quot;Aptos&quot;,469777842,&quot;&quot;,469777843,&quot;Aptos&quot;,469777844,&quot;Aptos&quot;,201341986,&quot;1&quot;,469769226,&quot;Aptos&quot;,268442635,&quot;22&quot;,469775450,&quot;normaltextrun&quot;,201340122,&quot;1&quot;,134233614,&quot;true&quot;,469778129,&quot;normaltextrun&quot;,335572020,&quot;1&quot;,469778324,&quot;Default Paragraph Font&quot;]}\">A neurologic examination can\u202f<\/span><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"normaltextrun\">determine<\/span><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"normaltextrun\">\u202fwhether a person has symptoms typical of <\/span><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"normaltextrun\">SCA12<\/span><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"normaltextrun\">.<\/span><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"textrun\" data-ccp-charstyle-defn=\"{&quot;ObjectId&quot;:&quot;884ca0a2-3096-4dd9-b9ad-d857f553f4df|106&quot;,&quot;ClassId&quot;:1073872969,&quot;Properties&quot;:[201342446,&quot;1&quot;,201342447,&quot;5&quot;,201342448,&quot;1&quot;,201342449,&quot;1&quot;,469777841,&quot;Aptos&quot;,469777842,&quot;&quot;,469777843,&quot;Aptos&quot;,469777844,&quot;Aptos&quot;,201341986,&quot;1&quot;,469769226,&quot;Aptos&quot;,268442635,&quot;22&quot;,469775450,&quot;textrun&quot;,201340122,&quot;1&quot;,134233614,&quot;true&quot;,469778129,&quot;textrun&quot;,335572020,&quot;1&quot;,469778324,&quot;Default Paragraph Font&quot;]}\">\u202f<\/span><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"normaltextrun\">This suspected diagnosis is then confirmed through brain imaging, such as MRI, and genetic testing to\u202fdetect the presence of the<\/span><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"textrun\">\u202f<\/span><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"normaltextrun\">abnormal gene that causes <\/span><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"normaltextrun\">SCA12<\/span><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"normaltextrun\">. A neurologist is often the most helpful specialist in recognizing symptoms and diagnosing the disease that\u202fcauses Ataxia.<\/span><span class=\"NormalTextRun SCXW88890573 BCX0\" data-ccp-charstyle=\"eop\" data-ccp-charstyle-defn=\"{&quot;ObjectId&quot;:&quot;884ca0a2-3096-4dd9-b9ad-d857f553f4df|108&quot;,&quot;ClassId&quot;:1073872969,&quot;Properties&quot;:[201342446,&quot;1&quot;,201342447,&quot;5&quot;,201342448,&quot;1&quot;,201342449,&quot;1&quot;,469777841,&quot;Aptos&quot;,469777842,&quot;&quot;,469777843,&quot;Aptos&quot;,469777844,&quot;Aptos&quot;,201341986,&quot;1&quot;,469769226,&quot;Aptos&quot;,268442635,&quot;22&quot;,469775450,&quot;eop&quot;,201340122,&quot;1&quot;,134233614,&quot;true&quot;,469778129,&quot;eop&quot;,335572020,&quot;1&quot;,469778324,&quot;Default Paragraph Font&quot;]}\">\u202f<\/span><\/span><span class=\"EOP SCXW88890573 BCX0\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7a6d3cb elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7a6d3cb\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-117bfab\" data-id=\"117bfab\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b39053b elementor-widget elementor-widget-spacer\" data-id=\"b39053b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-746ec5a elementor-widget elementor-widget-menu-anchor\" data-id=\"746ec5a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"SCA8SCAsource\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-494a4f1 elementor-widget elementor-widget-heading\" data-id=\"494a4f1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">SCA12 Research News<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-551196d elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"551196d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3f99a04 elementor-widget elementor-widget-text-editor\" data-id=\"3f99a04\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>SCAsource provides Ataxia research news, directly from researchers to the Ataxia community. <span style=\"color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Visit\u00a0<\/span><strong><span style=\"text-decoration: underline;\"><a href=\"https:\/\/www.ataxia.org\/SCAsource\" target=\"_blank\" rel=\"noopener\">SCAsource<\/a><\/span><\/strong><span style=\"color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\"> to see their full collection.\u00a0<\/span>Here is a collection of articles relevant to SCA12.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a8c5b58 elementor-grid-3 elementor-grid-tablet-2 elementor-grid-mobile-1 elementor-posts--thumbnail-top elementor-widget elementor-widget-posts\" data-id=\"a8c5b58\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;classic_columns&quot;:&quot;3&quot;,&quot;classic_columns_tablet&quot;:&quot;2&quot;,&quot;classic_columns_mobile&quot;:&quot;1&quot;,&quot;classic_row_gap&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:35,&quot;sizes&quot;:[]},&quot;classic_row_gap_laptop&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;classic_row_gap_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"posts.classic\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-posts-container elementor-posts elementor-posts--skin-classic elementor-grid\" role=\"list\">\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-22620 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-english tag-speech-language-pathology tag-symptoms tag-talking\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-intelligibility\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img decoding=\"async\" width=\"300\" height=\"157\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/11\/Jan-19-SCAsource-Image-300x157.png\" class=\"attachment-medium size-medium wp-image-22621\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/11\/Jan-19-SCAsource-Image-300x157.png 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/11\/Jan-19-SCAsource-Image-1024x536.png 1024w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/11\/Jan-19-SCAsource-Image-768x402.png 768w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/11\/Jan-19-SCAsource-Image.png 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-intelligibility\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is intelligibility?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>Speech intelligibility refers to how many words can be correctly understood by a listener. For example, if someone says the phrase, \u201cMy name is John,\u201d and a listener hears, \u201cMy <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-intelligibility\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-22277 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-english tag-speech-language-pathology tag-symptoms tag-talking\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-prosody\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img decoding=\"async\" width=\"300\" height=\"157\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/10\/Nov-10-Featured-Image-Sized-300x157.png\" class=\"attachment-medium size-medium wp-image-22284\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/10\/Nov-10-Featured-Image-Sized-300x157.png 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/10\/Nov-10-Featured-Image-Sized-1024x536.png 1024w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/10\/Nov-10-Featured-Image-Sized-768x402.png 768w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2023\/10\/Nov-10-Featured-Image-Sized.png 1200w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-prosody\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is prosody?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>Speech not only consists of the words we say, but how we say them. That \u201chow\u201d is what is called prosody: the pitch, loudness, and timing of speech. The term <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-prosody\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-19472 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-article-summary tag-ataxia tag-english tag-patient-research tag-unknown-ataxia-type tag-wearable-technologies\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/sara-home\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"200\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/05\/shutterstock_664160281-768x512-1-300x200.webp\" class=\"attachment-medium size-medium wp-image-19512\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/05\/shutterstock_664160281-768x512-1-300x200.webp 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/05\/shutterstock_664160281-768x512-1.webp 768w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/sara-home\/\" target=&quot;_blank&quot;>\n\t\t\t\tScientists develop a new approach to assessing Ataxia at home\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>Written by Ziyang Zhao Edited by Dr. Hayley McLoughlin A newly developed smartphone application will allow patients to assess ataxia at home. There\u2019s an interesting problem in science that\u2019s often <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/sara-home\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-19465 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-aso-treatment tag-ataxia tag-biomarker tag-clinical-research tag-english tag-patient-research tag-research-methods\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-cerebrospinal-fluid-csf\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"297\" height=\"300\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/shutterstock_1143762689-edited-768x775-1-297x300.webp\" class=\"attachment-medium size-medium wp-image-19589\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/shutterstock_1143762689-edited-768x775-1-297x300.webp 297w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/shutterstock_1143762689-edited-768x775-1-45x45.webp 45w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/shutterstock_1143762689-edited-768x775-1.webp 768w\" sizes=\"(max-width: 297px) 100vw, 297px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-cerebrospinal-fluid-csf\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is Cerebrospinal Fluid (CSF)?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>Public transit may not be the first thing that comes to mind when we think about the brain, but it\u2019s a great way to understand how all the parts of <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-cerebrospinal-fluid-csf\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-19451 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-dna tag-english tag-genetic-testing\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-a-gene\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"288\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/Gene1-768x736-1-300x288.webp\" class=\"attachment-medium size-medium wp-image-19548\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/Gene1-768x736-1-300x288.webp 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/Gene1-768x736-1.webp 768w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-a-gene\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is a Gene?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>A gene is the basic physical unitof heredity. Every living cell contains genetic information that determines an organism\u2019s development, form, and function. This genetic information is encoded by two macromolecules: <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-a-gene\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<article class=\"elementor-post elementor-grid-item post-19406 scasourceposts type-scasourceposts status-publish has-post-thumbnail hentry category-scasource-snapshot tag-ataxia tag-dna tag-english tag-genetic-testing tag-polyglutamine-diseases\" role=\"listitem\">\n\t\t\t\t<a class=\"elementor-post__thumbnail__link\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-polyglutamine-expansion\/\" tabindex=\"-1\" target=&quot;_blank&quot;>\n\t\t\t<div class=\"elementor-post__thumbnail\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"205\" src=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/13062715825_8d7331ce40_o-300x205.jpg\" class=\"attachment-medium size-medium wp-image-19675\" alt=\"\" srcset=\"https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/13062715825_8d7331ce40_o-300x205.jpg 300w, https:\/\/www.ataxia.org\/wp-content\/uploads\/2022\/07\/13062715825_8d7331ce40_o.jpg 683w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/div>\n\t\t<\/a>\n\t\t\t\t<div class=\"elementor-post__text\">\n\t\t\t\t<h3 class=\"elementor-post__title\">\n\t\t\t<a href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-polyglutamine-expansion\/\" target=&quot;_blank&quot;>\n\t\t\t\tSnapshot: What is Polyglutamine Expansion?\t\t\t<\/a>\n\t\t<\/h3>\n\t\t\t\t<div class=\"elementor-post__excerpt\">\n\t\t\t<p>The information that allows the normal development and functioning of each human being is coded in DNA, which exists in all cells of the body. Several successive segments of DNA <a class=\"MoreInfo\" href=\"https:\/\/www.ataxia.org\/scasourceposts\/snapshot-what-is-polyglutamine-expansion\/\">Read More&#8230;<\/a><\/p>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/article>\n\t\t\t\t<\/div>\n\t\t\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f9f1b8d elementor-widget elementor-widget-spacer\" data-id=\"f9f1b8d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>SCA12 A collection of resources for individuals and families affected by Spinocerebellar Ataxia Type 12 (SCA12). 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